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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa)    
Predicted Functional Partners:
tdk
Thymidine kinase.
  
 
 0.980
C821_01401
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
 
 0.964
C821_01153
Thymidylate synthase.
  
 
 0.959
C821_01560
ComE operon protein 2.
    
 0.958
C821_00523
Hypothetical protein.
  
 
 0.956
C821_01363
DNA polymerase III subunit delta'.
  
 
 0.949
C821_01152
Thymidylate synthase.
  
 
 0.922
C821_01362
Initiation-control protein yabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
    0.876
C821_01364
Hypothetical protein.
 
    0.860
rsmI
16S rRNA (-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
    0.834
Your Current Organism:
Lactobacillus sp. ASF360
NCBI taxonomy Id: 97137
Other names: L. sp. ASF360
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.