| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C821_00771 | C821_01617 | C821_00771 | C821_01617 | Carbamoyl-phosphate synthase, small subunit. | Carbamoyl-phosphate synthase large chain. | 0.985 |
| C821_00771 | C821_01618 | C821_00771 | C821_01618 | Carbamoyl-phosphate synthase, small subunit. | Carbamoyl-phosphate synthase large chain. | 0.999 |
| C821_00771 | C821_01621 | C821_00771 | C821_01621 | Carbamoyl-phosphate synthase, small subunit. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.999 |
| C821_00771 | C821_01622 | C821_00771 | C821_01622 | Carbamoyl-phosphate synthase, small subunit. | Hypothetical protein. | 0.870 |
| C821_00771 | glmS | C821_00771 | C821_01093 | Carbamoyl-phosphate synthase, small subunit. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.896 |
| C821_00771 | pyrC | C821_00771 | C821_01620 | Carbamoyl-phosphate synthase, small subunit. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.995 |
| C821_00771 | pyrD | C821_00771 | C821_01624 | Carbamoyl-phosphate synthase, small subunit. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.824 |
| C821_00771 | pyrE | C821_00771 | C821_01626 | Carbamoyl-phosphate synthase, small subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.771 |
| C821_00771 | pyrF | C821_00771 | C821_01625 | Carbamoyl-phosphate synthase, small subunit. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.939 |
| C821_01617 | C821_00771 | C821_01617 | C821_00771 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase, small subunit. | 0.985 |
| C821_01617 | C821_01618 | C821_01617 | C821_01618 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase large chain. | 0.961 |
| C821_01617 | C821_01621 | C821_01617 | C821_01621 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.988 |
| C821_01617 | C821_01622 | C821_01617 | C821_01622 | Carbamoyl-phosphate synthase large chain. | Hypothetical protein. | 0.805 |
| C821_01617 | carA | C821_01617 | C821_01619 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.994 |
| C821_01617 | glmS | C821_01617 | C821_01093 | Carbamoyl-phosphate synthase large chain. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.871 |
| C821_01617 | pyrC | C821_01617 | C821_01620 | Carbamoyl-phosphate synthase large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.963 |
| C821_01617 | pyrD | C821_01617 | C821_01624 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.925 |
| C821_01617 | pyrE | C821_01617 | C821_01626 | Carbamoyl-phosphate synthase large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.909 |
| C821_01617 | pyrF | C821_01617 | C821_01625 | Carbamoyl-phosphate synthase large chain. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.932 |
| C821_01618 | C821_00771 | C821_01618 | C821_00771 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase, small subunit. | 0.999 |