| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C820_00343 | C820_00346 | C820_00343 | C820_00346 | Precorrin-4 C11-methyltransferase. | Precorrin-6x reductase. | 0.999 |
| C820_00343 | C820_02809 | C820_00343 | C820_02809 | Precorrin-4 C11-methyltransferase. | Hypothetical protein; Belongs to the ALAD family. | 0.685 |
| C820_00343 | C820_02810 | C820_00343 | C820_02810 | Precorrin-4 C11-methyltransferase. | uroporphyrinogen-III C-methyltransferase. | 0.903 |
| C820_00343 | C820_02812 | C820_00343 | C820_02812 | Precorrin-4 C11-methyltransferase. | Siroheme synthase domain-containing protein. | 0.757 |
| C820_00343 | hemC | C820_00343 | C820_02811 | Precorrin-4 C11-methyltransferase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.723 |
| C820_00346 | C820_00343 | C820_00346 | C820_00343 | Precorrin-6x reductase. | Precorrin-4 C11-methyltransferase. | 0.999 |
| C820_00346 | C820_01102 | C820_00346 | C820_01102 | Precorrin-6x reductase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.693 |
| C820_00346 | C820_02809 | C820_00346 | C820_02809 | Precorrin-6x reductase. | Hypothetical protein; Belongs to the ALAD family. | 0.655 |
| C820_00346 | C820_02810 | C820_00346 | C820_02810 | Precorrin-6x reductase. | uroporphyrinogen-III C-methyltransferase. | 0.886 |
| C820_00346 | C820_02812 | C820_00346 | C820_02812 | Precorrin-6x reductase. | Siroheme synthase domain-containing protein. | 0.973 |
| C820_00346 | hemC | C820_00346 | C820_02811 | Precorrin-6x reductase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.678 |
| C820_00346 | nadE | C820_00346 | C820_02814 | Precorrin-6x reductase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.442 |
| C820_01102 | C820_00346 | C820_01102 | C820_00346 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Precorrin-6x reductase. | 0.693 |
| C820_01102 | C820_02809 | C820_01102 | C820_02809 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Belongs to the ALAD family. | 0.674 |
| C820_01102 | C820_02810 | C820_01102 | C820_02810 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | uroporphyrinogen-III C-methyltransferase. | 0.660 |
| C820_01102 | hemC | C820_01102 | C820_02811 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.451 |
| C820_01102 | kbl | C820_01102 | C820_02305 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.711 |
| C820_01102 | nadE | C820_01102 | C820_02814 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.825 |
| C820_01102 | polA | C820_01102 | C820_01025 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.785 |
| C820_01102 | ribBA | C820_01102 | C820_01100 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |