Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DFL_008635Uncharacterized protein. (854 aa)    
Predicted Functional Partners:
DFL_002596
Histone H2A; Belongs to the histone H2A family.
    
 0.735
DFL_009565
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.734
DFL_000203
Histone H2B; Belongs to the histone H2B family.
    
 0.717
DFL_001956
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
 
 0.694
DFL_000188
Uncharacterized protein.
    
 
 0.686
DFL_005859
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.680
DFL_004081
Uncharacterized protein.
    
 0.680
DFL_007715
Uncharacterized protein.
    
  0.675
DFL_005680
Uncharacterized protein.
   
 0.675
DFL_005545
Plus3 domain-containing protein.
    
 
 0.666
Your Current Organism:
Arthrobotrys flagrans
NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.