node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DFL_001342 | DFL_003295 | A0A437AGZ9 | A0A437A1E9 | Uncharacterized protein. | PAT1 domain-containing protein. | 0.975 |
DFL_001342 | DFL_004833 | A0A437AGZ9 | A0A437A5T0 | Uncharacterized protein. | Uncharacterized protein. | 0.989 |
DFL_001342 | DFL_006712 | A0A437AGZ9 | A0A436ZTV7 | Uncharacterized protein. | Nudix hydrolase domain-containing protein. | 0.802 |
DFL_001342 | DFL_006879 | A0A437AGZ9 | A0A436ZUL4 | Uncharacterized protein. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.967 |
DFL_001342 | DFL_009630 | A0A437AGZ9 | A0A436ZS69 | Uncharacterized protein. | 5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. | 0.991 |
DFL_001342 | LSM1 | A0A437AGZ9 | A0A436ZUB9 | Uncharacterized protein. | U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. | 0.856 |
DFL_001342 | LSM4 | A0A437AGZ9 | A0A437AEM9 | Uncharacterized protein. | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.889 |
DFL_002274 | DFL_004032 | A0A437AA80 | A0A437A3L2 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.893 |
DFL_002274 | DFL_006712 | A0A437AA80 | A0A436ZTV7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nudix hydrolase domain-containing protein. | 0.701 |
DFL_002274 | DFL_008981 | A0A437AA80 | A0A436ZQE9 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.867 |
DFL_003295 | DFL_001342 | A0A437A1E9 | A0A437AGZ9 | PAT1 domain-containing protein. | Uncharacterized protein. | 0.975 |
DFL_003295 | DFL_004833 | A0A437A1E9 | A0A437A5T0 | PAT1 domain-containing protein. | Uncharacterized protein. | 0.976 |
DFL_003295 | DFL_006712 | A0A437A1E9 | A0A436ZTV7 | PAT1 domain-containing protein. | Nudix hydrolase domain-containing protein. | 0.779 |
DFL_003295 | DFL_006879 | A0A437A1E9 | A0A436ZUL4 | PAT1 domain-containing protein. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.900 |
DFL_003295 | DFL_009630 | A0A437A1E9 | A0A436ZS69 | PAT1 domain-containing protein. | 5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. | 0.959 |
DFL_003295 | LSM1 | A0A437A1E9 | A0A436ZUB9 | PAT1 domain-containing protein. | U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. | 0.998 |
DFL_003295 | LSM4 | A0A437A1E9 | A0A437AEM9 | PAT1 domain-containing protein. | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.997 |
DFL_004032 | DFL_002274 | A0A437A3L2 | A0A437AA80 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.893 |
DFL_004032 | DFL_006712 | A0A437A3L2 | A0A436ZTV7 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nudix hydrolase domain-containing protein. | 0.734 |
DFL_004032 | DFL_008981 | A0A437A3L2 | A0A436ZQE9 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.872 |