STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DFL_007941Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (341 aa)    
Predicted Functional Partners:
DFL_000545
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 0.998
DFL_006409
Uncharacterized protein.
   
 0.988
DFL_007791
Protein kinase domain-containing protein.
    
 
 0.967
DFL_006201
Uncharacterized protein.
    
 0.966
DFL_001818
Lipase_3 domain-containing protein.
   
 
 0.961
DFL_008617
ATG16 domain-containing protein.
   
 0.947
DFL_009601
Autophagy-related protein.
   
 0.931
DFL_000237
Uncharacterized protein.
   
 0.925
DFL_006895
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.922
DFL_006355
Phosphatidylinositol 3-kinase VPS34.
    
 0.830
Your Current Organism:
Arthrobotrys flagrans
NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans
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