STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DFL_005859Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (227 aa)    
Predicted Functional Partners:
DFL_005656
Uncharacterized protein.
    
  0.994
DFL_000203
Histone H2B; Belongs to the histone H2B family.
 
 
 0.993
DFL_000204
Histone H2A; Belongs to the histone H2A family.
 
 
 0.986
DFL_002596
Histone H2A; Belongs to the histone H2A family.
 
 
 0.971
DFL_004033
Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.
    
 0.970
DFL_003537
Histone H3; Belongs to the histone H3 family.
 
 
 0.968
DFL_009629
WD_REPEATS_REGION domain-containing protein.
    
 0.964
DFL_005209
Uncharacterized protein.
    
 0.964
DFL_007716
Histone domain-containing protein.
 
 
 0.963
DFL_005187
WD_REPEATS_REGION domain-containing protein.
    
 0.948
Your Current Organism:
Arthrobotrys flagrans
NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.