DFL_006242 protein (Arthrobotrys flagrans) - STRING interaction network

Nodes:

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second shell of interactors

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Edges:

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

DFL_006242

CBM1 domain-containing protein. (460 aa)

Predicted Functional Partners:

DFL_009629

0.737

DFL_003519

0.505

DFL_001916

0.505

DFL_000510

0.505

DFL_006965

0.478

DFL_008514

0.464

DFL_009093

0.460

DFL_004801

0.458

DFL_001081

0.458

DFL_002572

0.446

Your Current Organism:

Arthrobotrys flagrans

NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DFL_000510	DFL_003519	A0A437AEG4	A0A437A227	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.856
DFL_000510	DFL_006242	A0A437AEG4	A0A437A0K5	Protein kinase domain-containing protein.	CBM1 domain-containing protein.	0.505
DFL_001081	DFL_002572	A0A437AG48	A0A437AAV7	Uncharacterized protein.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.995
DFL_001081	DFL_004801	A0A437AG48	A0A437A675	Uncharacterized protein.	Ribosomal_L18e/L15P domain-containing protein.	0.996
DFL_001081	DFL_006242	A0A437AG48	A0A437A0K5	Uncharacterized protein.	CBM1 domain-containing protein.	0.458
DFL_001081	DFL_006965	A0A437AG48	A0A436ZUW5	Uncharacterized protein.	Uncharacterized protein; Belongs to the bacterial ribosomal protein bS18 family.	0.998
DFL_001081	DFL_008514	A0A437AG48	A0A436ZP07	Uncharacterized protein.	AAA domain-containing protein.	0.923
DFL_001081	DFL_009093	A0A437AG48	A0A436ZQN8	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family.	0.998
DFL_001916	DFL_003519	A0A437A981	A0A437A227	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.851
DFL_001916	DFL_006242	A0A437A981	A0A437A0K5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CBM1 domain-containing protein.	0.505
DFL_002572	DFL_001081	A0A437AAV7	A0A437AG48	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.995
DFL_002572	DFL_004801	A0A437AAV7	A0A437A675	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Ribosomal_L18e/L15P domain-containing protein.	0.936
DFL_002572	DFL_006242	A0A437AAV7	A0A437A0K5	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	CBM1 domain-containing protein.	0.446
DFL_002572	DFL_006965	A0A437AAV7	A0A436ZUW5	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein; Belongs to the bacterial ribosomal protein bS18 family.	0.967
DFL_002572	DFL_008514	A0A437AAV7	A0A436ZP07	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	AAA domain-containing protein.	0.596
DFL_002572	DFL_009093	A0A437AAV7	A0A436ZQN8	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family.	0.961
DFL_003519	DFL_000510	A0A437A227	A0A437AEG4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.856
DFL_003519	DFL_001916	A0A437A227	A0A437A981	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.851
DFL_003519	DFL_006242	A0A437A227	A0A437A0K5	Protein kinase domain-containing protein.	CBM1 domain-containing protein.	0.505
DFL_004801	DFL_001081	A0A437A675	A0A437AG48	Ribosomal_L18e/L15P domain-containing protein.	Uncharacterized protein.	0.996

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.781

expected number of edges:

11

PPI enrichment p-value:

0.00219

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009167

Purine ribonucleoside monophosphate metabolic process

5 of 11

1.93

2.86

4.00e-07

GO:0009150

Purine ribonucleotide metabolic process

8 of 49

1.49

2.33

2.79e-08

GO:0009165

Nucleotide biosynthetic process

8 of 60

1.4

2.12

2.79e-08

GO:0009132

Nucleoside diphosphate metabolic process

4 of 14

1.73

1.95

3.70e-05

GO:0046037

GMP metabolic process

3 of 5

2.05

1.92

0.00015

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019205

Nucleobase-containing compound kinase activity

3 of 11

1.71

0.97

0.0112

GO:0004748

Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

2 of 2

2.27

0.93

0.0189

GO:0004385

Guanylate kinase activity

2 of 2

2.27

0.93

0.0189

GO:0106130

Purine phosphoribosyltransferase activity

2 of 4

1.97

0.91

0.0189

GO:0016776

Phosphotransferase activity, phosphate group as acceptor

3 of 15

1.57

0.89

0.0144

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005971

Ribonucleoside-diphosphate reductase complex

2 of 2

2.27

0.98

0.0153

GO:0005737

Cytoplasm

10 of 713

0.42

0.31

0.0153

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:673

Mixed, incl. Purine nucleoside monophosphate metabolic process, and Ribonucleoside hydrolase-like

7 of 21

1.8

3.37

1.38e-09

CL:676

Purine nucleoside monophosphate metabolic process, and Ribonucleoside hydrolase-like

6 of 14

1.9

3.33

1.26e-08

CL:671

Mixed, incl. Nucleoside monophosphate metabolic process, and Pteridine-containing compound metabolic process

9 of 40

1.62

3.24

2.71e-11

CL:678

Purine nucleoside monophosphate biosynthetic process

2 of 6

1.8

0.69

0.0475

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

11 of 72

1.46

2.97

2.17e-14

map00240

Pyrimidine metabolism

3 of 43

1.12

0.55

0.0489

map01100

Metabolic pathways

11 of 614

0.53

0.46

8.76e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

3 of 19

1.47

1.05

0.0042

MAP-168256

Immune System

3 of 24

1.37

1.0

0.0042

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005971

Ribonucleoside-diphosphate reductase complex

2 of 2

2.27

0.82

0.0314

GOCC:0005622

Intracellular

10 of 759

0.39

0.28

0.0362

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0328

Glycosyltransferase

3 of 11

1.71

1.08

0.0063

KW-0660

Purine salvage

2 of 3

2.1

0.9

0.0205

KW-0808

Transferase

6 of 223

0.7

0.43

0.0264

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029057

Phosphoribosyltransferase-like

3 of 10

1.75

0.81

0.0266

IPR000836

Phosphoribosyltransferase domain

3 of 10

1.75

0.81

0.0266

IPR008145

Guanylate kinase/L-type calcium channel beta subunit

2 of 2

2.27

0.74

0.0438

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00072

Guanylate kinase homologues.

2 of 2

2.27

1.04

0.0116

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