STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DFL_003541Uncharacterized protein. (1040 aa)    
Predicted Functional Partners:
DFL_003572
Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 0.997
DFL_006222
DNA helicase; Belongs to the MCM family.
   
 
 0.986
DFL_008769
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 
 0.971
DFL_004252
DNA helicase; Belongs to the MCM family.
   
 
 0.969
DFL_002677
WD_REPEATS_REGION domain-containing protein.
   
 
 0.969
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.968
DFL_003407
Uncharacterized protein.
   
 
 0.968
DFL_002186
DNA helicase; Belongs to the MCM family.
   
 
 0.963
DFL_005947
DNA helicase; Belongs to the MCM family.
   
 
 0.962
DFL_004255
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 
 0.962
Your Current Organism:
Arthrobotrys flagrans
NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.