| node1 | node2 | node1 annotation | node2 annotation | score |
| A0A550BY70 | A0A550C5Y3 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.943 |
| A0A550BY70 | A0A550C7M0 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Tryptophan synthase. | 0.971 |
| A0A550BY70 | A0A550CAM2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Pyridoxal phosphate-dependent transferase. | 0.863 |
| A0A550BY70 | A0A550CK85 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Pyridoxal phosphate-dependent transferase. | 0.971 |
| A0A550BY70 | A0A550CLB7 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Tryptophan synthase beta subunit-like PLP-dependent enzyme. | 0.958 |
| A0A550BY70 | A0A550CQ12 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Threonine synthase. | 0.453 |
| A0A550BY70 | A0A550CSG4 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Histidine biosynthesis trifunctional protein. | 0.713 |
| A0A550BY70 | A0A550CXU3 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Tryptophan synthase beta subunit-like PLP-dependent enzyme. | 0.614 |
| A0A550BY70 | A0A550CZQ4 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | Tryptophan synthase beta subunit-like PLP-dependent enzyme. | 0.614 |
| A0A550C5Y3 | A0A550BY70 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.943 |
| A0A550C5Y3 | A0A550C7M0 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Tryptophan synthase. | 0.980 |
| A0A550C5Y3 | A0A550CAM2 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Pyridoxal phosphate-dependent transferase. | 0.997 |
| A0A550C5Y3 | A0A550CK85 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Pyridoxal phosphate-dependent transferase. | 0.911 |
| A0A550C5Y3 | A0A550CLB7 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Tryptophan synthase beta subunit-like PLP-dependent enzyme. | 0.821 |
| A0A550C5Y3 | A0A550CQ12 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Threonine synthase. | 0.683 |
| A0A550C5Y3 | A0A550CSG4 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histidine biosynthesis trifunctional protein. | 0.875 |
| A0A550C5Y3 | A0A550CXU3 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Tryptophan synthase beta subunit-like PLP-dependent enzyme. | 0.660 |
| A0A550C5Y3 | A0A550CZQ4 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Tryptophan synthase beta subunit-like PLP-dependent enzyme. | 0.660 |
| A0A550C7M0 | A0A550BY70 | Tryptophan synthase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.971 |
| A0A550C7M0 | A0A550C5Y3 | Tryptophan synthase. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.980 |