| node1 | node2 | node1 annotation | node2 annotation | score |
| A0A550C5Y2 | A0A550C6C6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Pyridoxal phosphate-dependent transferase. | 0.984 |
| A0A550C5Y2 | A0A550CA40 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Inositol-1-monophosphatase. | 0.687 |
| A0A550C5Y2 | A0A550CD35 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Imidazoleglycerol-phosphate dehydratase-domain-containing protein. | 0.994 |
| A0A550C5Y2 | A0A550CJH3 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Uncharacterized protein. | 0.985 |
| A0A550C5Y2 | A0A550CNZ2 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | SNF2 family N-terminal domain-containing protein. | 0.949 |
| A0A550C5Y2 | A0A550CS39 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.992 |
| A0A550C5Y2 | A0A550CSG4 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Histidine biosynthesis trifunctional protein. | 0.999 |
| A0A550C5Y2 | A0A550CU56 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.529 |
| A0A550C5Y2 | A0A550CWM7 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.908 |
| A0A550C6C6 | A0A550C5Y2 | Pyridoxal phosphate-dependent transferase. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.984 |
| A0A550C6C6 | A0A550CA40 | Pyridoxal phosphate-dependent transferase. | Inositol-1-monophosphatase. | 0.897 |
| A0A550C6C6 | A0A550CD35 | Pyridoxal phosphate-dependent transferase. | Imidazoleglycerol-phosphate dehydratase-domain-containing protein. | 0.998 |
| A0A550C6C6 | A0A550CJH3 | Pyridoxal phosphate-dependent transferase. | Uncharacterized protein. | 0.973 |
| A0A550C6C6 | A0A550CNZ2 | Pyridoxal phosphate-dependent transferase. | SNF2 family N-terminal domain-containing protein. | 0.957 |
| A0A550C6C6 | A0A550CS39 | Pyridoxal phosphate-dependent transferase. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.959 |
| A0A550C6C6 | A0A550CSG4 | Pyridoxal phosphate-dependent transferase. | Histidine biosynthesis trifunctional protein. | 0.998 |
| A0A550C6C6 | A0A550CU56 | Pyridoxal phosphate-dependent transferase. | Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.917 |
| A0A550C6C6 | A0A550CWM7 | Pyridoxal phosphate-dependent transferase. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.909 |
| A0A550C952 | A0A550CD35 | Uncharacterized protein. | Imidazoleglycerol-phosphate dehydratase-domain-containing protein. | 0.888 |
| A0A550CA40 | A0A550C5Y2 | Inositol-1-monophosphatase. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.687 |