node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ESR1 | ESR2 | ENSTTRP00000002811 | ENSTTRP00000000485 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Estrogen receptor beta isoform X2. | 0.991 |
ESR1 | JUN | ENSTTRP00000002811 | ENSTTRP00000010932 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Transcription factor AP-1; Belongs to the bZIP family. | 0.978 |
ESR1 | MED1 | ENSTTRP00000002811 | ENSTTRP00000008003 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.980 |
ESR1 | NCOA1 | ENSTTRP00000002811 | ENSTTRP00000014337 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor coactivator. | 0.996 |
ESR1 | NCOA2 | ENSTTRP00000002811 | ENSTTRP00000012347 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor coactivator. | 0.994 |
ESR1 | NCOA3 | ENSTTRP00000002811 | ENSTTRP00000000019 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor coactivator. | 0.996 |
ESR1 | PRMT1 | ENSTTRP00000002811 | ENSTTRP00000005225 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Protein arginine methyltransferase 1. | 0.953 |
ESR1 | PTGES3 | ENSTTRP00000002811 | ENSTTRP00000002014 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Prostaglandin E synthase 3 isoform X1. | 0.960 |
ESR1 | SRC | ENSTTRP00000002811 | ENSTTRP00000005378 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Proto-oncogene tyrosine-protein kinase Src. | 0.997 |
ESR1 | STRN | ENSTTRP00000002811 | ENSTTRP00000008086 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Striatin. | 0.969 |
ESR2 | ESR1 | ENSTTRP00000000485 | ENSTTRP00000002811 | Estrogen receptor beta isoform X2. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.991 |
ESR2 | JUN | ENSTTRP00000000485 | ENSTTRP00000010932 | Estrogen receptor beta isoform X2. | Transcription factor AP-1; Belongs to the bZIP family. | 0.958 |
ESR2 | MED1 | ENSTTRP00000000485 | ENSTTRP00000008003 | Estrogen receptor beta isoform X2. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.954 |
ESR2 | NCOA1 | ENSTTRP00000000485 | ENSTTRP00000014337 | Estrogen receptor beta isoform X2. | Nuclear receptor coactivator. | 0.992 |
ESR2 | NCOA2 | ENSTTRP00000000485 | ENSTTRP00000012347 | Estrogen receptor beta isoform X2. | Nuclear receptor coactivator. | 0.968 |
ESR2 | NCOA3 | ENSTTRP00000000485 | ENSTTRP00000000019 | Estrogen receptor beta isoform X2. | Nuclear receptor coactivator. | 0.972 |
ESR2 | PRMT1 | ENSTTRP00000000485 | ENSTTRP00000005225 | Estrogen receptor beta isoform X2. | Protein arginine methyltransferase 1. | 0.955 |
ESR2 | PTGES3 | ENSTTRP00000000485 | ENSTTRP00000002014 | Estrogen receptor beta isoform X2. | Prostaglandin E synthase 3 isoform X1. | 0.954 |
ESR2 | SRC | ENSTTRP00000000485 | ENSTTRP00000005378 | Estrogen receptor beta isoform X2. | Proto-oncogene tyrosine-protein kinase Src. | 0.956 |
ESR2 | STRN | ENSTTRP00000000485 | ENSTTRP00000008086 | Estrogen receptor beta isoform X2. | Striatin. | 0.951 |