STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101325394Interferon-activable protein 203-like isoform X2. (488 aa)    
Predicted Functional Partners:
STING1
Stimulator of interferon genes protein isoform X1.
   
 0.973
PYCARD
PYD and CARD domain containing.
   
 0.930
DDX41
Probable ATP-dependent RNA helicase DDX41 isoform X1.
    
 0.740
CGAS
Cyclic GMP-AMP synthase isoform X1.
    
 
 0.720
IRF7
Interferon regulatory factor 7.
   
  
 0.692
IRF3
Interferon regulatory factor 3.
     
 0.679
BRCA1
Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]
    
 
 0.655
TP53BP1
Tumor suppressor p53-binding protein 1 isoform X1.
    
 0.637
CASP1
Caspase-1; Belongs to the peptidase C14A family.
   
 
 0.605
TBK1
Serine/threonine-protein kinase TBK1 isoform X1.
   
 
 0.603
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.