STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNAI1Snail family transcriptional repressor 1. (264 aa)    
Predicted Functional Partners:
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.885
KPNB1
Importin subunit beta-1.
    
   0.846
RCOR1
REST corepressor 1.
    
 0.824
BTRC
F-box/WD repeat-containing protein 1A isoform X1.
    
 
 0.768
ZEB1
Zinc finger E-box-binding homeobox 1 isoform X1.
      
0.763
HDAC1
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.762
CDH1
Cadherin-1 isoform X1; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.757
CDH2
Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.752
SMAD3
Mothers against decapentaplegic homolog 3.
    
 
 0.746
VIM
Vimentin; Belongs to the intermediate filament family.
      
 0.740
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.