STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL23Kelch-like protein 23 isoform X1. (558 aa)    
Predicted Functional Partners:
CUL3
Cullin-3 isoform X1; Belongs to the cullin family.
    
 0.693
USP28
Ubiquitin carboxyl-terminal hydrolase 28 isoform X7; Belongs to the peptidase C19 family.
    
 
 0.684
UBXN7
UBX domain-containing protein 7.
    
  0.574
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.548
BBS9
Protein PTHB1 isoform X1.
    
 0.545
TRIM55
Tripartite motif-containing protein 55 isoform X1.
    
 
 0.527
TTC8
Tetratricopeptide repeat protein 8.
    
  0.522
SNX16
Sorting nexin-16 isoform X1.
      
 0.507
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.506
DCDC2
Doublecortin domain-containing protein 2.
      
 0.505
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.