STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARNpoly(A)-specific ribonuclease PARN isoform X2. (627 aa)    
Predicted Functional Partners:
DCP2
m7GpppN-mRNA hydrolase isoform X1.
     
 0.980
PNLDC1
poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform X2.
  
  
0.879
EXOSC5
Exosome complex component RRP46.
     
 0.795
KHSRP
KH-type splicing regulatory protein.
    
 0.786
EXOSC3
Exosome complex component RRP40 isoform X1.
     
 0.781
EXOSC7
Exosome complex component RRP42.
     
 0.772
NOCT
Nocturnin.
      
 0.751
SYMPK
Symplekin.
    
 
 0.717
DIS3L2
DIS3-like exonuclease 2 isoform X2.
     
 0.686
RTEL1
Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]
   
  
 0.676
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.