STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP12Caspase 12 (gene/pseudogene). (333 aa)    
Predicted Functional Partners:
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.873
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.869
ENSTTRP00000006141
annotation not available
   
 0.865
CASP7
Caspase-7; Belongs to the peptidase C14A family.
   
0.862
CAPN1
Calpain-1 catalytic subunit isoform X2; Belongs to the peptidase C2 family.
    
 0.855
CAPN2
Calpain-2 catalytic subunit; Belongs to the peptidase C2 family.
    
 0.848
CASP1
Caspase-1; Belongs to the peptidase C14A family.
   
 
 
0.847
PYCARD
PYD and CARD domain containing.
   
 0.820
GSDMD
Gasdermin D.
    
 0.810
CAPN8
Calpain 8.
    
 0.786
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.