STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITKTyrosine-protein kinase. (620 aa)    
Predicted Functional Partners:
LCP2
Lymphocyte cytosolic protein 2 isoform X4.
   
 0.986
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.971
PLCG1
Phosphoinositide phospholipase C.
   
 0.955
CD3E
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.951
HCK
Tyrosine-protein kinase.
  
0.933
TXK
Tyrosine-protein kinase.
  
 
 
0.925
VAV2
Vav guanine nucleotide exchange factor 2.
   
 0.922
VAV3
Guanine nucleotide exchange factor VAV3.
   
 0.920
FGR
Tyrosine-protein kinase.
  
 
0.916
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
    
 0.916
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.