STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (368 aa)    
Predicted Functional Partners:
ARID4B
AT-rich interactive domain-containing protein 4B isoform X1.
    
 0.945
ARID4A
AT-rich interactive domain-containing protein 4A isoform X2.
    
 0.945
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 0.909
HDAC9
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
  
 
0.904
SUDS3
Sin3 histone deacetylase corepressor complex component SDS3 isoform X3.
    
 0.895
H2AZ1
Histone H2A; Belongs to the histone H2A family.
   
 0.894
MACROH2A1
Histone H2A; Belongs to the histone H2A family.
    
 0.892
MACROH2A2
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
    
 0.892
HDAC4
Histone deacetylase 4.
  
 
0.889
LEO1
RNA polymerase-associated protein LEO1 isoform X1.
    
 0.889
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.