FLOT2 protein (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FLOT2

Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (482 aa)

Predicted Functional Partners:

FLOT1

0.983

SORBS1

0.890

CAV1

0.829

CAV2

0.729

EEA1

0.724

STOM

0.722

CD63

0.722

CAV3

0.697

PKNOX2

0.681

PHB2

0.656

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	CAV2	ENSTTRP00000008073	ENSTTRP00000008061	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.999
CAV1	CAV3	ENSTTRP00000008073	ENSTTRP00000005705	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.951
CAV1	CD63	ENSTTRP00000008073	ENSTTRP00000009210	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	CD63 molecule.	0.495
CAV1	EEA1	ENSTTRP00000008073	ENSTTRP00000001345	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Early endosome antigen 1 isoform X2.	0.791
CAV1	FLOT1	ENSTTRP00000008073	ENSTTRP00000007896	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.837
CAV1	FLOT2	ENSTTRP00000008073	ENSTTRP00000003870	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.829
CAV1	STOM	ENSTTRP00000008073	ENSTTRP00000005046	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Erythrocyte band 7 integral membrane protein.	0.466
CAV2	CAV1	ENSTTRP00000008061	ENSTTRP00000008073	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.999
CAV2	CAV3	ENSTTRP00000008061	ENSTTRP00000005705	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.991
CAV2	CD63	ENSTTRP00000008061	ENSTTRP00000009210	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	CD63 molecule.	0.416
CAV2	EEA1	ENSTTRP00000008061	ENSTTRP00000001345	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Early endosome antigen 1 isoform X2.	0.680
CAV2	FLOT1	ENSTTRP00000008061	ENSTTRP00000007896	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.738
CAV2	FLOT2	ENSTTRP00000008061	ENSTTRP00000003870	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.729
CAV3	CAV1	ENSTTRP00000005705	ENSTTRP00000008073	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.951
CAV3	CAV2	ENSTTRP00000005705	ENSTTRP00000008061	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.991
CAV3	EEA1	ENSTTRP00000005705	ENSTTRP00000001345	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Early endosome antigen 1 isoform X2.	0.561
CAV3	FLOT1	ENSTTRP00000005705	ENSTTRP00000007896	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.729
CAV3	FLOT2	ENSTTRP00000005705	ENSTTRP00000003870	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.697
CAV3	STOM	ENSTTRP00000005705	ENSTTRP00000005046	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Erythrocyte band 7 integral membrane protein.	0.482
CD63	CAV1	ENSTTRP00000009210	ENSTTRP00000008073	CD63 molecule.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.495