SPG7 protein (Tursiops truncatus) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SPG7

LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family. (792 aa)

Predicted Functional Partners:

MAIP1

0.959

PHB

0.877

PHB2

0.875

CLPX

0.795

SPG21

0.790

LONP2

0.732

MRPL19

0.729

PMPCA

0.722

TRIM41

0.719

MRPL3

0.715

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPX	LONP2	ENSTTRP00000004708	ENSTTRP00000014405	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	0.954
CLPX	PHB	ENSTTRP00000004708	ENSTTRP00000010274	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.	Prohibitin.	0.518
CLPX	PHB2	ENSTTRP00000004708	ENSTTRP00000004531	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.	Prohibitin 2.	0.465
CLPX	SPG7	ENSTTRP00000004708	ENSTTRP00000004108	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.	LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family.	0.795
LONP2	CLPX	ENSTTRP00000014405	ENSTTRP00000004708	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.	0.954
LONP2	PMPCA	ENSTTRP00000014405	ENSTTRP00000007169	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	Mitochondrial-processing peptidase subunit alpha isoform X1; Belongs to the peptidase M16 family.	0.415
LONP2	SPG7	ENSTTRP00000014405	ENSTTRP00000004108	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1.	LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family.	0.732
MAIP1	PHB	ENSTTRP00000015379	ENSTTRP00000010274	m-AAA protease-interacting protein 1, mitochondrial isoform X1.	Prohibitin.	0.677
MAIP1	PHB2	ENSTTRP00000015379	ENSTTRP00000004531	m-AAA protease-interacting protein 1, mitochondrial isoform X1.	Prohibitin 2.	0.672
MAIP1	PMPCA	ENSTTRP00000015379	ENSTTRP00000007169	m-AAA protease-interacting protein 1, mitochondrial isoform X1.	Mitochondrial-processing peptidase subunit alpha isoform X1; Belongs to the peptidase M16 family.	0.588
MAIP1	SPG7	ENSTTRP00000015379	ENSTTRP00000004108	m-AAA protease-interacting protein 1, mitochondrial isoform X1.	LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family.	0.959
MRPL19	MRPL3	ENSTTRP00000013351	ENSTTRP00000009878	39S ribosomal protein L19, mitochondrial.	39S ribosomal protein L3, mitochondrial isoform X1; Belongs to the universal ribosomal protein uL3 family.	0.999
MRPL19	SPG7	ENSTTRP00000013351	ENSTTRP00000004108	39S ribosomal protein L19, mitochondrial.	LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family.	0.729
MRPL3	MRPL19	ENSTTRP00000009878	ENSTTRP00000013351	39S ribosomal protein L3, mitochondrial isoform X1; Belongs to the universal ribosomal protein uL3 family.	39S ribosomal protein L19, mitochondrial.	0.999
MRPL3	SPG7	ENSTTRP00000009878	ENSTTRP00000004108	39S ribosomal protein L3, mitochondrial isoform X1; Belongs to the universal ribosomal protein uL3 family.	LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family.	0.715
PHB	CLPX	ENSTTRP00000010274	ENSTTRP00000004708	Prohibitin.	ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.	0.518
PHB	MAIP1	ENSTTRP00000010274	ENSTTRP00000015379	Prohibitin.	m-AAA protease-interacting protein 1, mitochondrial isoform X1.	0.677
PHB	PHB2	ENSTTRP00000010274	ENSTTRP00000004531	Prohibitin.	Prohibitin 2.	0.999
PHB	PMPCA	ENSTTRP00000010274	ENSTTRP00000007169	Prohibitin.	Mitochondrial-processing peptidase subunit alpha isoform X1; Belongs to the peptidase M16 family.	0.783
PHB	SPG7	ENSTTRP00000010274	ENSTTRP00000004108	Prohibitin.	LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family.	0.877