STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2374 aa)    
Predicted Functional Partners:
SPTAN1
Spectrin alpha chain, non-erythrocytic 1 isoform X1.
   
0.932
SPTA1
Spectrin alpha chain, erythrocytic 1 isoform X2.
   
0.841
ITSN2
Intersectin-2 isoform X1.
     
 0.669
ENSTTRP00000000512
annotation not available
   
 0.614
ANK2
Ankyrin-2.
   
 0.614
ANK1
Ankyrin 1.
   
 0.614
ANK3
Ankyrin-3 isoform X4.
   
 0.614
ANKRD60
Ankyrin repeat domain-containing protein 60.
   
 0.586
ANKDD1B
Ankyrin repeat and death domain containing 1B.
   
 0.575
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.570
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.