STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (816 aa)    
Predicted Functional Partners:
OTUD6B
LOW QUALITY PROTEIN: OTU domain-containing protein 6B.
      
 0.728
FAXC
Failed axon connections homolog.
      
 0.680
AP4E1
AP-4 complex subunit epsilon-1 isoform X1.
   
    0.650
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
    
 0.622
XRN1
5'-3' exoribonuclease 1.
   
    0.608
RBMX
RNA-binding motif protein, X chromosome.
    
 
 0.602
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
  0.592
PNISR
Arginine/serine-rich protein PNISR isoform X1.
 
 
  
 0.583
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.577
OTULIN
Ubiquitin thioesterase otulin isoform X1.
      
 0.562
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.