STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZMAT3Zinc finger matrin-type protein 3 isoform X1. (283 aa)    
Predicted Functional Partners:
AEN
Apoptosis-enhancing nuclease.
      
 0.764
GRB2
Growth factor receptor-bound protein 2.
    
 0.621
MAPK12
Mitogen-activated protein kinase.
    
 0.594
MAPK11
Mitogen-activated protein kinase.
    
 0.594
MAPK14
Mitogen-activated protein kinase 14.
    
 0.594
MAPK13
Mitogen-activated protein kinase.
    
 0.594
HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]
    
 0.583
CBLB
E3 ubiquitin-protein ligase CBL-B.
    
  0.544
CBL
E3 ubiquitin-protein ligase CBL.
    
  0.544
EPS15L1
LOW QUALITY PROTEIN: epidermal growth factor receptor substrate 15-like 1.
    
  0.541
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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