STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPEF1Serine/threonine-protein phosphatase with EF-hands. (650 aa)    
Predicted Functional Partners:
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Signaling mediates the activation of phospholipase C (By similarity). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
   
 0.935
PPP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1.
    
 0.746
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
   
 0.724
PPP2R2B
Protein phosphatase 2 regulatory subunit Bbeta.
   
 0.691
PPP2R2A
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
   
 0.691
IGBP1
Immunoglobulin-binding protein 1 isoform X1.
    
 0.686
WDR82
WD repeat-containing protein 82 isoform X1.
    
 0.654
ITSN2
Intersectin-2 isoform X1.
   
 0.648
ANAPC1
Anaphase-promoting complex subunit 1 isoform X1.
    
 0.646
CPSF1
Cleavage and polyadenylation specificity factor subunit 1.
    
 0.626
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.