node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATG2B | EPG5 | ENSTTRP00000004655 | ENSTTRP00000005067 | Autophagy-related protein 2 homolog B isoform X5. | Ectopic P granules protein 5 homolog. | 0.622 |
ATG2B | RILP | ENSTTRP00000004655 | ENSTTRP00000006494 | Autophagy-related protein 2 homolog B isoform X5. | Rab-interacting lysosomal protein. | 0.545 |
ATM | ENSTTRP00000011017 | ENSTTRP00000005735 | ENSTTRP00000011017 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | annotation not available | 0.731 |
ATM | EPG5 | ENSTTRP00000005735 | ENSTTRP00000005067 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Ectopic P granules protein 5 homolog. | 0.802 |
ATM | FAT1 | ENSTTRP00000005735 | ENSTTRP00000000883 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Protocadherin Fat 1 isoform X2. | 0.742 |
ATM | SYNE1 | ENSTTRP00000005735 | ENSTTRP00000002826 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Nesprin-1 isoform X1. | 0.746 |
ENSTTRP00000011017 | ATM | ENSTTRP00000011017 | ENSTTRP00000005735 | annotation not available | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.731 |
ENSTTRP00000011017 | EPG5 | ENSTTRP00000011017 | ENSTTRP00000005067 | annotation not available | Ectopic P granules protein 5 homolog. | 0.788 |
ENSTTRP00000011017 | FAT1 | ENSTTRP00000011017 | ENSTTRP00000000883 | annotation not available | Protocadherin Fat 1 isoform X2. | 0.769 |
ENSTTRP00000011017 | SYNE1 | ENSTTRP00000011017 | ENSTTRP00000002826 | annotation not available | Nesprin-1 isoform X1. | 0.765 |
EPG5 | ATG2B | ENSTTRP00000005067 | ENSTTRP00000004655 | Ectopic P granules protein 5 homolog. | Autophagy-related protein 2 homolog B isoform X5. | 0.622 |
EPG5 | ATM | ENSTTRP00000005067 | ENSTTRP00000005735 | Ectopic P granules protein 5 homolog. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.802 |
EPG5 | ENSTTRP00000011017 | ENSTTRP00000005067 | ENSTTRP00000011017 | Ectopic P granules protein 5 homolog. | annotation not available | 0.788 |
EPG5 | FAT1 | ENSTTRP00000005067 | ENSTTRP00000000883 | Ectopic P granules protein 5 homolog. | Protocadherin Fat 1 isoform X2. | 0.796 |
EPG5 | PLEKHM1 | ENSTTRP00000005067 | ENSTTRP00000013863 | Ectopic P granules protein 5 homolog. | Pleckstrin homology and RUN domain containing M1. | 0.744 |
EPG5 | PSTPIP2 | ENSTTRP00000005067 | ENSTTRP00000012458 | Ectopic P granules protein 5 homolog. | Proline-serine-threonine phosphatase-interacting protein 2 isoform X1. | 0.697 |
EPG5 | RILP | ENSTTRP00000005067 | ENSTTRP00000006494 | Ectopic P granules protein 5 homolog. | Rab-interacting lysosomal protein. | 0.691 |
EPG5 | SYNE1 | ENSTTRP00000005067 | ENSTTRP00000002826 | Ectopic P granules protein 5 homolog. | Nesprin-1 isoform X1. | 0.601 |
EPG5 | TECPR2 | ENSTTRP00000005067 | ENSTTRP00000015242 | Ectopic P granules protein 5 homolog. | Tectonin beta-propeller repeat-containing protein 2 isoform X2. | 0.799 |
EPG5 | VPS39 | ENSTTRP00000005067 | ENSTTRP00000002398 | Ectopic P granules protein 5 homolog. | vam6/Vps39-like protein isoform X1. | 0.591 |