node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BHMT2 | CTH | ENSTTRP00000012297 | ENSTTRP00000012340 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Cystathionine gamma-lyase isoform X3. | 0.937 |
BHMT2 | MOCOS | ENSTTRP00000012297 | ENSTTRP00000006755 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.923 |
BHMT2 | TST | ENSTTRP00000012297 | ENSTTRP00000001025 | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | Sulfurtransferase. | 0.580 |
CTH | BHMT2 | ENSTTRP00000012340 | ENSTTRP00000012297 | Cystathionine gamma-lyase isoform X3. | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | 0.937 |
CTH | MOCOS | ENSTTRP00000012340 | ENSTTRP00000006755 | Cystathionine gamma-lyase isoform X3. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.892 |
CTH | NFS1 | ENSTTRP00000012340 | ENSTTRP00000016150 | Cystathionine gamma-lyase isoform X3. | Cysteine desulfurase, mitochondrial. | 0.722 |
CTH | SCLY | ENSTTRP00000012340 | ENSTTRP00000009565 | Cystathionine gamma-lyase isoform X3. | Selenocysteine lyase. | 0.731 |
CTH | TST | ENSTTRP00000012340 | ENSTTRP00000001025 | Cystathionine gamma-lyase isoform X3. | Sulfurtransferase. | 0.958 |
CTH | TSTD1 | ENSTTRP00000012340 | ENSTTRP00000008660 | Cystathionine gamma-lyase isoform X3. | Thiosulfate sulfurtransferase like domain containing 1. | 0.818 |
GPHN | MOCOS | ENSTTRP00000014963 | ENSTTRP00000006755 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.960 |
GPHN | SEPHS1 | ENSTTRP00000014963 | ENSTTRP00000010539 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Selenide, water dikinase 1 isoform X1. | 0.625 |
GPHN | TSTD1 | ENSTTRP00000014963 | ENSTTRP00000008660 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Thiosulfate sulfurtransferase like domain containing 1. | 0.569 |
ISCU | MOCOS | ENSTTRP00000003794 | ENSTTRP00000006755 | Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.999 |
ISCU | NFS1 | ENSTTRP00000003794 | ENSTTRP00000016150 | Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Cysteine desulfurase, mitochondrial. | 0.999 |
ISCU | NFU1 | ENSTTRP00000003794 | ENSTTRP00000014521 | Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1. | 0.874 |
ISCU | SCLY | ENSTTRP00000003794 | ENSTTRP00000009565 | Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Selenocysteine lyase. | 0.998 |
ISCU | TST | ENSTTRP00000003794 | ENSTTRP00000001025 | Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Sulfurtransferase. | 0.512 |
ISCU | TSTD1 | ENSTTRP00000003794 | ENSTTRP00000008660 | Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | Thiosulfate sulfurtransferase like domain containing 1. | 0.927 |
MOCOS | BHMT2 | ENSTTRP00000006755 | ENSTTRP00000012297 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | S-methylmethionine--homocysteine S-methyltransferase BHMT2; Involved in the regulation of homocysteine metabolism. | 0.923 |
MOCOS | CTH | ENSTTRP00000006755 | ENSTTRP00000012340 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | Cystathionine gamma-lyase isoform X3. | 0.892 |