STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDK4Protein-serine/threonine kinase. (407 aa)    
Predicted Functional Partners:
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.843
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1.
    
 0.826
PDHX
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.826
CKMT2
Creatine kinase S-type, mitochondrial; Belongs to the ATP:guanido phosphotransferase family.
      
 0.808
AGL
Glycogen debranching enzyme.
   
  
 0.807
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.769
CPXM1
Probable carboxypeptidase X1 isoform X1.
      
 0.760
MAP3K4
Mitogen-activated protein kinase kinase kinase 4 isoform X1.
    
 0.747
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.746
DLD
Dihydrolipoyl dehydrogenase.
    
 0.705
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.