STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X8.
   
 0.987
UBE2A
Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.852
UBR4
E3 ubiquitin-protein ligase UBR4 isoform X8.
   
  
 0.816
UBE2B
Ubiquitin-conjugating enzyme E2 B isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.815
MRI1
Methylthioribose-1-phosphate isomerase isoform X2; Belongs to the eIF-2B alpha/beta/delta subunits family.
      
 0.794
MYSM1
Myb like, SWIRM and MPN domains 1.
   
  
 0.766
USP34
Ubiquitin carboxyl-terminal hydrolase 34 isoform X2; Belongs to the peptidase C19 family.
   
    0.750
UBR5
E3 ubiquitin-protein ligase UBR5 isoform X1.
   
  
 0.710
WAC
WW domain-containing adapter protein with coiled-coil isoform X3.
   
  
 0.703
UBE2U
Ubiquitin-conjugating enzyme E2 U isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.700
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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