node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNR1 | CNR2 | ENSTTRP00000009110 | ENSTTRP00000015298 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.923 |
CNR1 | DRD2 | ENSTTRP00000009110 | ENSTTRP00000006948 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.921 |
CNR1 | ENSTTRP00000015348 | ENSTTRP00000009110 | ENSTTRP00000015348 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | annotation not available | 0.919 |
CNR1 | GNAI1 | ENSTTRP00000009110 | ENSTTRP00000006121 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein G(I) subunit alpha-1. | 0.929 |
CNR1 | GNAI2 | ENSTTRP00000009110 | ENSTTRP00000007306 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit alpha i2. | 0.929 |
CNR1 | GNAI3 | ENSTTRP00000009110 | ENSTTRP00000001378 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit alpha i3. | 0.929 |
CNR1 | GNB2 | ENSTTRP00000009110 | ENSTTRP00000005832 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | G protein subunit beta 2. | 0.919 |
CNR1 | GNB4 | ENSTTRP00000009110 | ENSTTRP00000001481 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein subunit beta-4. | 0.919 |
CNR1 | GNB5 | ENSTTRP00000009110 | ENSTTRP00000004413 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein subunit beta-5. | 0.918 |
CNR1 | GNG4 | ENSTTRP00000009110 | ENSTTRP00000007365 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.919 |
CNR2 | CNR1 | ENSTTRP00000015298 | ENSTTRP00000009110 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] | 0.923 |
CNR2 | DRD2 | ENSTTRP00000015298 | ENSTTRP00000006948 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.695 |
CNR2 | ENSTTRP00000015348 | ENSTTRP00000015298 | ENSTTRP00000015348 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | annotation not available | 0.555 |
CNR2 | GNAI1 | ENSTTRP00000015298 | ENSTTRP00000006121 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(I) subunit alpha-1. | 0.577 |
CNR2 | GNAI2 | ENSTTRP00000015298 | ENSTTRP00000007306 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i2. | 0.577 |
CNR2 | GNAI3 | ENSTTRP00000015298 | ENSTTRP00000001378 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i3. | 0.577 |
CNR2 | GNB2 | ENSTTRP00000015298 | ENSTTRP00000005832 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | G protein subunit beta 2. | 0.555 |
CNR2 | GNB4 | ENSTTRP00000015298 | ENSTTRP00000001481 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit beta-4. | 0.555 |
CNR2 | GNB5 | ENSTTRP00000015298 | ENSTTRP00000004413 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit beta-5. | 0.691 |
CNR2 | GNG4 | ENSTTRP00000015298 | ENSTTRP00000007365 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.604 |