STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAG3Lymphocyte activation gene 3 protein. (458 aa)    
Predicted Functional Partners:
CTLA4
Cytotoxic T-lymphocyte protein 4.
    
 
 0.763
TIGIT
T-cell immunoreceptor with Ig and ITIM domains.
      
 0.719
ICOS
Inducible T-cell costimulator.
      
 0.544
CD4
Tursiops truncatus CD4 molecule (CD4), mRNA.
      
 0.516
FOXP3
Forkhead box P3.
      
 0.512
PTK7
Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.509
PDCD1
Programmed cell death 1.
    
 0.478
NUTM1
NUT family member 1.
  
 
  0.467
CBY2
LOW QUALITY PROTEIN: spermatid-associated protein.
  
 
   0.425
EGFLAM
Pikachurin.
    
  0.411
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (30%) [HD]