node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC45 | GINS1 | ENSTTRP00000014172 | ENSTTRP00000001542 | Cell division control protein 45 homolog. | DNA replication complex GINS protein PSF1 isoform X3. | 0.992 |
CDC45 | GINS4 | ENSTTRP00000014172 | ENSTTRP00000003336 | Cell division control protein 45 homolog. | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.995 |
CDC45 | MCM2 | ENSTTRP00000014172 | ENSTTRP00000016215 | Cell division control protein 45 homolog. | Minichromosome maintenance complex component 2. | 0.999 |
CDC45 | MCM4 | ENSTTRP00000014172 | ENSTTRP00000007880 | Cell division control protein 45 homolog. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC45 | MCM6 | ENSTTRP00000014172 | ENSTTRP00000003455 | Cell division control protein 45 homolog. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC45 | MCM7 | ENSTTRP00000014172 | ENSTTRP00000011680 | Cell division control protein 45 homolog. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
CDC45 | RPA3 | ENSTTRP00000014172 | ENSTTRP00000012930 | Cell division control protein 45 homolog. | Replication protein A 14 kDa subunit. | 0.833 |
CDC45 | TIMELESS | ENSTTRP00000014172 | ENSTTRP00000006785 | Cell division control protein 45 homolog. | Protein timeless homolog isoform X2. | 0.969 |
CDC45 | TIPIN | ENSTTRP00000014172 | ENSTTRP00000009659 | Cell division control protein 45 homolog. | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.966 |
CDC45 | WDHD1 | ENSTTRP00000014172 | ENSTTRP00000003111 | Cell division control protein 45 homolog. | WD repeat and HMG-box DNA-binding protein 1 isoform X1. | 0.995 |
GINS1 | CDC45 | ENSTTRP00000001542 | ENSTTRP00000014172 | DNA replication complex GINS protein PSF1 isoform X3. | Cell division control protein 45 homolog. | 0.992 |
GINS1 | GINS4 | ENSTTRP00000001542 | ENSTTRP00000003336 | DNA replication complex GINS protein PSF1 isoform X3. | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.999 |
GINS1 | MCM2 | ENSTTRP00000001542 | ENSTTRP00000016215 | DNA replication complex GINS protein PSF1 isoform X3. | Minichromosome maintenance complex component 2. | 0.993 |
GINS1 | MCM4 | ENSTTRP00000001542 | ENSTTRP00000007880 | DNA replication complex GINS protein PSF1 isoform X3. | DNA helicase; Belongs to the MCM family. | 0.997 |
GINS1 | MCM6 | ENSTTRP00000001542 | ENSTTRP00000003455 | DNA replication complex GINS protein PSF1 isoform X3. | DNA helicase; Belongs to the MCM family. | 0.981 |
GINS1 | MCM7 | ENSTTRP00000001542 | ENSTTRP00000011680 | DNA replication complex GINS protein PSF1 isoform X3. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.989 |
GINS1 | TIMELESS | ENSTTRP00000001542 | ENSTTRP00000006785 | DNA replication complex GINS protein PSF1 isoform X3. | Protein timeless homolog isoform X2. | 0.922 |
GINS1 | TIPIN | ENSTTRP00000001542 | ENSTTRP00000009659 | DNA replication complex GINS protein PSF1 isoform X3. | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.958 |
GINS1 | WDHD1 | ENSTTRP00000001542 | ENSTTRP00000003111 | DNA replication complex GINS protein PSF1 isoform X3. | WD repeat and HMG-box DNA-binding protein 1 isoform X1. | 0.964 |
GINS4 | CDC45 | ENSTTRP00000003336 | ENSTTRP00000014172 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | Cell division control protein 45 homolog. | 0.995 |