AKAP4 protein (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AKAP4

LOW QUALITY PROTEIN: A-kinase anchor protein 4. (855 aa)

Predicted Functional Partners:

SPAG6

0.767

QRICH2

0.758

CFAP44

0.750

CFAP43

0.720

DUSP18

0.686

PLCZ1

0.684

GAS8

0.683

ACRBP

0.683

GAPDHS

0.683

TSSK6

0.682

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACRBP	AKAP4	ENSTTRP00000011141	ENSTTRP00000009887	Acrosin binding protein.	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	0.683
AKAP4	ACRBP	ENSTTRP00000009887	ENSTTRP00000011141	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Acrosin binding protein.	0.683
AKAP4	CFAP43	ENSTTRP00000009887	ENSTTRP00000005339	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Cilia- and flagella-associated protein 43.	0.720
AKAP4	CFAP44	ENSTTRP00000009887	ENSTTRP00000005513	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Cilia- and flagella-associated protein 44.	0.750
AKAP4	DUSP18	ENSTTRP00000009887	ENSTTRP00000009693	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Dual specificity protein phosphatase 18; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.686
AKAP4	GAPDHS	ENSTTRP00000009887	ENSTTRP00000014338	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.683
AKAP4	GAS8	ENSTTRP00000009887	ENSTTRP00000004731	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Growth arrest-specific protein 8 isoform X1.	0.683
AKAP4	PLCZ1	ENSTTRP00000009887	ENSTTRP00000002795	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Phosphoinositide phospholipase C.	0.684
AKAP4	QRICH2	ENSTTRP00000009887	ENSTTRP00000015087	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Glutamine-rich protein 2.	0.758
AKAP4	SPAG6	ENSTTRP00000009887	ENSTTRP00000006194	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Sperm-associated antigen 6 isoform X1.	0.767
AKAP4	TSSK6	ENSTTRP00000009887	ENSTTRP00000009366	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily.	0.682
CFAP43	AKAP4	ENSTTRP00000005339	ENSTTRP00000009887	Cilia- and flagella-associated protein 43.	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	0.720
CFAP43	CFAP44	ENSTTRP00000005339	ENSTTRP00000005513	Cilia- and flagella-associated protein 43.	Cilia- and flagella-associated protein 44.	0.742
CFAP43	QRICH2	ENSTTRP00000005339	ENSTTRP00000015087	Cilia- and flagella-associated protein 43.	Glutamine-rich protein 2.	0.816
CFAP44	AKAP4	ENSTTRP00000005513	ENSTTRP00000009887	Cilia- and flagella-associated protein 44.	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	0.750
CFAP44	CFAP43	ENSTTRP00000005513	ENSTTRP00000005339	Cilia- and flagella-associated protein 44.	Cilia- and flagella-associated protein 43.	0.742
CFAP44	QRICH2	ENSTTRP00000005513	ENSTTRP00000015087	Cilia- and flagella-associated protein 44.	Glutamine-rich protein 2.	0.840
DUSP18	AKAP4	ENSTTRP00000009693	ENSTTRP00000009887	Dual specificity protein phosphatase 18; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	0.686
GAPDHS	AKAP4	ENSTTRP00000014338	ENSTTRP00000009887	Glyceraldehyde-3-phosphate dehydrogenase.	LOW QUALITY PROTEIN: A-kinase anchor protein 4.	0.683
GAPDHS	TSSK6	ENSTTRP00000014338	ENSTTRP00000009366	Glyceraldehyde-3-phosphate dehydrogenase.	Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily.	0.676