STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLECPlectin. (4664 aa)    
Predicted Functional Partners:
DST
Dystonin isoform X1.
     
0.976
JUP
Junction plakoglobin-like.
    
 0.971
ITGB4
Integrin beta-4.
  
 0.958
CASP8
Caspase-8 isoform X2; Belongs to the peptidase C14A family.
    
 0.931
COL17A1
Collagen alpha-1(XVII) chain.
    
 0.928
PARP10
Poly [ADP-ribose] polymerase.
 
    
 0.890
PKP2
Plakophilin-2.
   
 0.870
CNN2
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
      
 0.866
NRBP2
Nuclear receptor-binding protein 2.
      
 0.827
DSG2
Desmoglein-2 isoform X1.
   
 0.819
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.