STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)    
Predicted Functional Partners:
ZADH2
Prostaglandin reductase 3 isoform X1.
 
 
 0.917
PTGES
Prostaglandin E synthase.
     
 0.817
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
    
 0.808
HSDL2
Hydroxysteroid dehydrogenase-like protein 2 isoform X5.
  
 0.709
FITM1
Fat storage-inducing transmembrane protein 1.
      
 0.667
ECHS1
enoyl-CoA hydratase, short chain 1.
   
 0.666
ALDH7A1
Alpha-aminoadipic semialdehyde dehydrogenase isoform X1; Belongs to the aldehyde dehydrogenase family.
  
 0.652
LOC101323566
Aldo-keto reductase family 1 member C3 homolog.
   
 
 0.650
AACS
acetoacetyl-CoA synthetase.
    
 0.647
OXCT1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.639
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.