EIF4G3 protein (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EIF4G3

Eukaryotic translation initiation factor 4 gamma 3 isoform X4. (1581 aa)

Predicted Functional Partners:

EIF4E

0.995

EIF4A1

0.987

EIF4A2

0.979

EIF4E1B

0.974

EIF4E2

0.966

EIF3D

0.944

EIF4E3

0.930

EIF4G1

0.920

EIF4G2

0.902

PABPC1

0.896

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF3D	EIF4A1	ENSTTRP00000006284	ENSTTRP00000009680	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	0.932
EIF3D	EIF4A2	ENSTTRP00000006284	ENSTTRP00000015962	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic translation initiation factor 4A2.	0.818
EIF3D	EIF4E	ENSTTRP00000006284	ENSTTRP00000003956	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic translation initiation factor 4E isoform X2; Belongs to the eukaryotic initiation factor 4E family.	0.581
EIF3D	EIF4E2	ENSTTRP00000006284	ENSTTRP00000010350	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic translation initiation factor 4E type 2 isoform X1; Belongs to the eukaryotic initiation factor 4E family.	0.578
EIF3D	EIF4E3	ENSTTRP00000006284	ENSTTRP00000004843	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic translation initiation factor 4E type 3 isoform X2; Belongs to the eukaryotic initiation factor 4E family.	0.758
EIF3D	EIF4G1	ENSTTRP00000006284	ENSTTRP00000010666	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic translation initiation factor 4 gamma 1.	0.741
EIF3D	EIF4G2	ENSTTRP00000006284	ENSTTRP00000013326	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic translation initiation factor 4 gamma 2.	0.749
EIF3D	EIF4G3	ENSTTRP00000006284	ENSTTRP00000010702	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Eukaryotic translation initiation factor 4 gamma 3 isoform X4.	0.944
EIF3D	PABPC1	ENSTTRP00000006284	ENSTTRP00000004419	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.472
EIF4A1	EIF3D	ENSTTRP00000009680	ENSTTRP00000006284	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	0.932
EIF4A1	EIF4A2	ENSTTRP00000009680	ENSTTRP00000015962	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4A2.	0.988
EIF4A1	EIF4E	ENSTTRP00000009680	ENSTTRP00000003956	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E isoform X2; Belongs to the eukaryotic initiation factor 4E family.	0.967
EIF4A1	EIF4E1B	ENSTTRP00000009680	ENSTTRP00000013301	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E family member 1B.	0.866
EIF4A1	EIF4E2	ENSTTRP00000009680	ENSTTRP00000010350	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E type 2 isoform X1; Belongs to the eukaryotic initiation factor 4E family.	0.486
EIF4A1	EIF4E3	ENSTTRP00000009680	ENSTTRP00000004843	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4E type 3 isoform X2; Belongs to the eukaryotic initiation factor 4E family.	0.834
EIF4A1	EIF4G1	ENSTTRP00000009680	ENSTTRP00000010666	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4 gamma 1.	0.994
EIF4A1	EIF4G2	ENSTTRP00000009680	ENSTTRP00000013326	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4 gamma 2.	0.990
EIF4A1	EIF4G3	ENSTTRP00000009680	ENSTTRP00000010702	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4 gamma 3 isoform X4.	0.987
EIF4A1	PABPC1	ENSTTRP00000009680	ENSTTRP00000004419	Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.872
EIF4A2	EIF3D	ENSTTRP00000015962	ENSTTRP00000006284	Eukaryotic translation initiation factor 4A2.	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...]	0.818