STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)    
Predicted Functional Partners:
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family.
    
 0.977
PDPK1
3-phosphoinositide-dependent protein kinase 1 isoform X1.
    
0.972
FOXO1
Forkhead box protein O1.
    
 0.969
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
    
 0.969
PHLPP2
PH domain leucine-rich repeat-containing protein phosphatase 2 isoform X1.
    
 0.958
PIK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.
    
 0.956
FOXO3
Forkhead box protein O3.
    
 0.956
TSC2
Tuberin.
    
 0.955
TRIB3
Tribbles homolog 3.
 
  
 0.954
FOXO4
Forkhead box O4.
    
 0.954
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.