STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACAT1Cullin-5 isoform X7; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)    
Predicted Functional Partners:
HADH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform X1.
 
 0.991
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.990
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.990
ECI2
enoyl-CoA delta isomerase 2, mitochondrial.
  
 0.989
HADHA
Trifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.979
ACADSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1.
  
 0.970
EHHADH
Peroxisomal bifunctional enzyme.
 
 0.968
ACADS
acyl-CoA dehydrogenase short chain.
  
 0.965
HMGCL
hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1.
  
 
 0.962
OXCT1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
 
 
 0.960
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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