STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2F5Transcription factor E2F5 isoform X2. (340 aa)    
Predicted Functional Partners:
RBL1
Retinoblastoma-like protein 1 isoform X2.
   
 0.985
RBL2
Retinoblastoma-like protein 2.
   
 0.985
TFDP1
Transcription factor.
   
 0.983
TFDP2
Transcription factor.
   
 0.979
RB1
Retinoblastoma-associated protein.
   
 0.976
SMAD3
Mothers against decapentaplegic homolog 3.
    
 0.944
E2F4
LOW QUALITY PROTEIN: transcription factor E2F4.
  
 
0.940
SMAD4
Mothers against decapentaplegic homolog.
    
 0.929
SMAD2
Mothers against decapentaplegic homolog.
    
 0.920
E2F3
Transcription factor E2F3.
  
 
0.917
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.