STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (448 aa)    
Predicted Functional Partners:
AFP
Alpha-fetoprotein.
      
 0.782
PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1.
    
 
 0.769
HNF1A
HNF1 homeobox A.
   
 0.742
GSC
Homeobox protein goosecoid.
    
 
 0.693
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.649
NCOA1
Nuclear receptor coactivator.
    
 
 0.644
NR0B2
Nuclear receptor subfamily 0 group B member 2.
   
 0.632
NCOA2
Nuclear receptor coactivator.
    
 
 0.624
HNF1B
Hepatocyte nuclear factor 1-beta isoform X2.
   
 0.606
RPL9
60S ribosomal protein L9.
    
 0.602
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (22%) [HD]