STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF133E3 ubiquitin-protein ligase RNF133. (375 aa)    
Predicted Functional Partners:
OTUB1
Ubiquitin thioesterase OTUB1 isoform X2.
    
 0.656
USP8
Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family.
    
 0.607
OTUB2
Ubiquitin thioesterase OTUB2.
    
 0.596
ENSTTRP00000008305
annotation not available
    
 0.572
USP2
Ubiquitin carboxyl-terminal hydrolase 2; Belongs to the peptidase C19 family.
    
 0.450
USP21
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 0.450
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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