LTB protein (Tursiops truncatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

LTB

Lymphotoxin beta. (193 aa)

Predicted Functional Partners:

LTA

0.999

LTBR

0.992

TNFSF13B

0.783

CD40

0.728

MAP3K14

0.726

TNFRSF11B

0.712

CXCL13

0.712

CCR7

0.665

ARHGAP44

0.663

CD40LG

0.662

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP44	LTB	ENSTTRP00000002716	ENSTTRP00000013356	Rho GTPase activating protein 44.	Lymphotoxin beta.	0.663
CCR7	CD40	ENSTTRP00000016031	ENSTTRP00000000458	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	Tumor necrosis factor receptor superfamily member 5.	0.767
CCR7	CD40LG	ENSTTRP00000016031	ENSTTRP00000002135	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.685
CCR7	CXCL13	ENSTTRP00000016031	ENSTTRP00000005289	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine 13.	0.967
CCR7	LTA	ENSTTRP00000016031	ENSTTRP00000013350	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	Lymphotoxin alpha.	0.639
CCR7	LTB	ENSTTRP00000016031	ENSTTRP00000013356	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	Lymphotoxin beta.	0.665
CD40	CCR7	ENSTTRP00000000458	ENSTTRP00000016031	Tumor necrosis factor receptor superfamily member 5.	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	0.767
CD40	CD40LG	ENSTTRP00000000458	ENSTTRP00000002135	Tumor necrosis factor receptor superfamily member 5.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.999
CD40	CXCL13	ENSTTRP00000000458	ENSTTRP00000005289	Tumor necrosis factor receptor superfamily member 5.	C-X-C motif chemokine 13.	0.511
CD40	LTA	ENSTTRP00000000458	ENSTTRP00000013350	Tumor necrosis factor receptor superfamily member 5.	Lymphotoxin alpha.	0.760
CD40	LTB	ENSTTRP00000000458	ENSTTRP00000013356	Tumor necrosis factor receptor superfamily member 5.	Lymphotoxin beta.	0.728
CD40	LTBR	ENSTTRP00000000458	ENSTTRP00000013715	Tumor necrosis factor receptor superfamily member 5.	Tumor necrosis factor receptor superfamily member 3.	0.404
CD40	MAP3K14	ENSTTRP00000000458	ENSTTRP00000005951	Tumor necrosis factor receptor superfamily member 5.	Mitogen-activated protein kinase kinase kinase 14.	0.596
CD40	TNFSF13B	ENSTTRP00000000458	ENSTTRP00000012018	Tumor necrosis factor receptor superfamily member 5.	Tumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family.	0.753
CD40LG	CCR7	ENSTTRP00000002135	ENSTTRP00000016031	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	0.685
CD40LG	CD40	ENSTTRP00000002135	ENSTTRP00000000458	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor receptor superfamily member 5.	0.999
CD40LG	CXCL13	ENSTTRP00000002135	ENSTTRP00000005289	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	C-X-C motif chemokine 13.	0.590
CD40LG	LTA	ENSTTRP00000002135	ENSTTRP00000013350	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Lymphotoxin alpha.	0.777
CD40LG	LTB	ENSTTRP00000002135	ENSTTRP00000013356	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Lymphotoxin beta.	0.662
CD40LG	LTBR	ENSTTRP00000002135	ENSTTRP00000013715	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor receptor superfamily member 3.	0.887