STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (635 aa)    
Predicted Functional Partners:
OPRM1
Mu-type opioid receptor isoform X2; Belongs to the G-protein coupled receptor 1 family.
    
 0.907
ARRB1
Beta-arrestin-1.
    
 0.895
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Signaling mediates the activation of phospholipase C (By similarity). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
   
 0.836
ARRB2
Arrestin beta 2.
    
 0.827
CCR7
C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.
    
 0.825
ENSTTRP00000012200
annotation not available
    
 0.823
XCR1
Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
  0.818
CXCR5
C-X-C motif chemokine receptor 5.
    
  0.818
CCR9
C-C chemokine receptor type 9; Belongs to the G-protein coupled receptor 1 family.
    
  0.818
CXCR3
C-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family.
    
  0.818
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.