STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXW4F-box/WD repeat-containing protein 4 isoform X1. (407 aa)    
Predicted Functional Partners:
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.851
SKP1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.829
UBFD1
Ubiquitin domain-containing protein UBFD1 isoform X1.
      
 0.752
CUL3
Cullin-3 isoform X1; Belongs to the cullin family.
    
  0.725
FBXW5
F-box and WD repeat domain containing 5.
     
 0.712
DYNC1I1
Cytoplasmic dynein 1 intermediate chain 1.
      
 0.679
POLL
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
 
    
 0.632
TXNDC9
Thioredoxin domain-containing protein 9.
    
   0.617
FBXW2
F-box/WD repeat-containing protein 2 isoform X2.
     
 0.615
CACUL1
CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family.
    
  0.607
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.