STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK4P21 (RAC1) activated kinase 4. (591 aa)    
Predicted Functional Partners:
INKA1
Inka box actin regulator 1.
    
 
 0.999
CDC42
Cell division control protein 42 homolog.
    
 0.999
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
    
 0.999
RAC2
Ras-related C3 botulinum toxin substrate 1.
    
 0.956
RAC3
Ras-related C3 botulinum toxin substrate 1 isoform X2.
    
 0.947
NCK1
Cytoplasmic protein.
    
 0.945
NCK2
Cytoplasmic protein NCK2 isoform X4.
    
 0.945
ARHGEF6
Rho guanine nucleotide exchange factor 6 isoform X1.
    
 0.943
ARHGEF7
Rho guanine nucleotide exchange factor 7 isoform X8.
    
 0.943
ITSN2
Intersectin-2 isoform X1.
    
 0.937
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.