node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRG2 | ANO1 | ENSTTRP00000004715 | ENSTTRP00000001004 | Adhesion G-protein coupled receptor G2 isoform X2; Belongs to the G-protein coupled receptor 2 family. | Anoctamin. | 0.684 |
ADGRG2 | CFTR | ENSTTRP00000004715 | ENSTTRP00000016182 | Adhesion G-protein coupled receptor G2 isoform X2; Belongs to the G-protein coupled receptor 2 family. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | 0.408 |
ADGRG2 | SLC26A9 | ENSTTRP00000004715 | ENSTTRP00000014789 | Adhesion G-protein coupled receptor G2 isoform X2; Belongs to the G-protein coupled receptor 2 family. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.766 |
ANO1 | ADGRG2 | ENSTTRP00000001004 | ENSTTRP00000004715 | Anoctamin. | Adhesion G-protein coupled receptor G2 isoform X2; Belongs to the G-protein coupled receptor 2 family. | 0.684 |
ANO1 | CFTR | ENSTTRP00000001004 | ENSTTRP00000016182 | Anoctamin. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | 0.568 |
ANO1 | SLC26A9 | ENSTTRP00000001004 | ENSTTRP00000014789 | Anoctamin. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.692 |
ATP2B2 | SLC12A8 | ENSTTRP00000004148 | ENSTTRP00000016586 | ATPase plasma membrane Ca2+ transporting 2. | Solute carrier family 12 member 8. | 0.453 |
ATP2B2 | SLC26A9 | ENSTTRP00000004148 | ENSTTRP00000014789 | ATPase plasma membrane Ca2+ transporting 2. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.685 |
CFTR | ADGRG2 | ENSTTRP00000016182 | ENSTTRP00000004715 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | Adhesion G-protein coupled receptor G2 isoform X2; Belongs to the G-protein coupled receptor 2 family. | 0.408 |
CFTR | ANO1 | ENSTTRP00000016182 | ENSTTRP00000001004 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | Anoctamin. | 0.568 |
CFTR | SLC26A9 | ENSTTRP00000016182 | ENSTTRP00000014789 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.793 |
CFTR | SLC4A4 | ENSTTRP00000016182 | ENSTTRP00000007990 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | Anion exchange protein. | 0.554 |
CFTR | SLC4A8 | ENSTTRP00000016182 | ENSTTRP00000013137 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. | Anion exchange protein. | 0.483 |
KCNN4 | SLC26A9 | ENSTTRP00000006664 | ENSTTRP00000014789 | Intermediate conductance calcium-activated potassium channel protein 4. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.692 |
KCNN4 | SLC4A3 | ENSTTRP00000006664 | ENSTTRP00000000203 | Intermediate conductance calcium-activated potassium channel protein 4. | Solute carrier family 4 member 3. | 0.495 |
KCNN4 | SLC4A8 | ENSTTRP00000006664 | ENSTTRP00000013137 | Intermediate conductance calcium-activated potassium channel protein 4. | Anion exchange protein. | 0.508 |
SLC12A8 | ATP2B2 | ENSTTRP00000016586 | ENSTTRP00000004148 | Solute carrier family 12 member 8. | ATPase plasma membrane Ca2+ transporting 2. | 0.453 |
SLC12A8 | SLC26A9 | ENSTTRP00000016586 | ENSTTRP00000014789 | Solute carrier family 12 member 8. | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.609 |
SLC26A9 | ADGRG2 | ENSTTRP00000014789 | ENSTTRP00000004715 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Adhesion G-protein coupled receptor G2 isoform X2; Belongs to the G-protein coupled receptor 2 family. | 0.766 |
SLC26A9 | ANO1 | ENSTTRP00000014789 | ENSTTRP00000001004 | Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | Anoctamin. | 0.692 |