LOC101328420 protein (Tursiops truncatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

LOC101328420

Zinc finger protein 615 isoform X1. (741 aa)

Predicted Functional Partners:

ENSTTRP00000003942

0.605

AK9

0.605

CEP192

0.570

KIAA0319

0.565

SLC30A8

0.555

TUBD1

0.522

BLMH

0.495

TRIM28

0.452

DHX15

0.448

CTR9

0.447

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	CTR9	ENSTTRP00000003943	ENSTTRP00000011691	Adenylate kinase 9.	RNA polymerase-associated protein CTR9 homolog isoform X2.	0.506
AK9	ENSTTRP00000003942	ENSTTRP00000003943	ENSTTRP00000003942	Adenylate kinase 9.	annotation not available	0.998
AK9	LOC101328420	ENSTTRP00000003943	ENSTTRP00000015698	Adenylate kinase 9.	Zinc finger protein 615 isoform X1.	0.605
BLMH	KIAA0319	ENSTTRP00000015489	ENSTTRP00000015519	Bleomycin hydrolase; Belongs to the peptidase C1 family.	Dyslexia-associated protein KIAA0319 homolog.	0.418
BLMH	LOC101328420	ENSTTRP00000015489	ENSTTRP00000015698	Bleomycin hydrolase; Belongs to the peptidase C1 family.	Zinc finger protein 615 isoform X1.	0.495
BLMH	SLC30A8	ENSTTRP00000015489	ENSTTRP00000001838	Bleomycin hydrolase; Belongs to the peptidase C1 family.	Zinc transporter 8.	0.508
CEP192	KIAA0319	ENSTTRP00000006560	ENSTTRP00000015519	Centrosomal protein of 192 kDa isoform X2.	Dyslexia-associated protein KIAA0319 homolog.	0.566
CEP192	LOC101328420	ENSTTRP00000006560	ENSTTRP00000015698	Centrosomal protein of 192 kDa isoform X2.	Zinc finger protein 615 isoform X1.	0.570
CEP192	SLC30A8	ENSTTRP00000006560	ENSTTRP00000001838	Centrosomal protein of 192 kDa isoform X2.	Zinc transporter 8.	0.465
CEP192	TUBD1	ENSTTRP00000006560	ENSTTRP00000016317	Centrosomal protein of 192 kDa isoform X2.	Tubulin delta chain isoform X1; Belongs to the tubulin family.	0.573
CTR9	AK9	ENSTTRP00000011691	ENSTTRP00000003943	RNA polymerase-associated protein CTR9 homolog isoform X2.	Adenylate kinase 9.	0.506
CTR9	DHX15	ENSTTRP00000011691	ENSTTRP00000011109	RNA polymerase-associated protein CTR9 homolog isoform X2.	pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.	0.455
CTR9	ENSTTRP00000003942	ENSTTRP00000011691	ENSTTRP00000003942	RNA polymerase-associated protein CTR9 homolog isoform X2.	annotation not available	0.506
CTR9	LOC101328420	ENSTTRP00000011691	ENSTTRP00000015698	RNA polymerase-associated protein CTR9 homolog isoform X2.	Zinc finger protein 615 isoform X1.	0.447
DHX15	CTR9	ENSTTRP00000011109	ENSTTRP00000011691	pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.	RNA polymerase-associated protein CTR9 homolog isoform X2.	0.455
DHX15	LOC101328420	ENSTTRP00000011109	ENSTTRP00000015698	pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.	Zinc finger protein 615 isoform X1.	0.448
ENSTTRP00000003942	AK9	ENSTTRP00000003942	ENSTTRP00000003943	annotation not available	Adenylate kinase 9.	0.998
ENSTTRP00000003942	CTR9	ENSTTRP00000003942	ENSTTRP00000011691	annotation not available	RNA polymerase-associated protein CTR9 homolog isoform X2.	0.506
ENSTTRP00000003942	LOC101328420	ENSTTRP00000003942	ENSTTRP00000015698	annotation not available	Zinc finger protein 615 isoform X1.	0.605
KIAA0319	BLMH	ENSTTRP00000015519	ENSTTRP00000015489	Dyslexia-associated protein KIAA0319 homolog.	Bleomycin hydrolase; Belongs to the peptidase C1 family.	0.418

page 1 of 3

Network Stats

number of nodes:

8

number of edges:

12

average node degree:

3

avg. local clustering coefficient:

0.842

expected number of edges:

7

PPI enrichment p-value:

0.0565

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

7 of 123

1.49

2.13

3.86e-07

GO:0010467

Gene expression

9 of 261

1.27

1.79

4.51e-08

GO:0001682

tRNA 5-leader removal

2 of 2

2.73

1.53

0.0016

GO:0034641

Cellular nitrogen compound metabolic process

9 of 899

0.73

0.63

0.00024

GO:0044238

Primary metabolic process

9 of 1683

0.46

0.32

0.0227

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 60

1.8

3.34

2.02e-09

GO:0003723

RNA binding

9 of 133

1.56

2.96

7.81e-11

GO:0019843

rRNA binding

5 of 46

1.77

2.35

3.21e-06

GO:0000049

tRNA binding

4 of 25

1.94

2.24

1.87e-05

GO:0004526

Ribonuclease P activity

2 of 2

2.73

1.48

0.0020

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

7 of 67

1.75

3.24

1.78e-09

GO:1990904

Ribonucleoprotein complex

2 of 15

1.86

1.0

0.0114

GO:0005622

Intracellular anatomical structure

8 of 1601

0.43

0.28

0.0478

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:29866043

(2018) Distinctive characters of Nostoc genomes in cyanolichens.

3 of 38

1.63

1.07

0.0057

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3811

Ribosome

7 of 53

1.85

3.42

2.87e-09

CL:3785

Structural constituent of ribosome, and Regulation of translation

8 of 114

1.58

2.74

2.87e-09

CL:3813

Ribosome

4 of 33

1.82

2.05

3.08e-05

CL:3817

Large ribosomal subunit, and Ribosome

3 of 13

2.1

1.89

0.00019

CL:3879

Ribosome

3 of 19

1.93

1.64

0.00048

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

calo03010

Ribosome

7 of 56

1.83

3.61

3.88e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

4 of 42

1.71

1.61

0.00030

GOCC:0043232

Intracellular non-membrane-bounded organelle

5 of 239

1.05

0.81

0.0032

GOCC:0043229

Intracellular organelle

7 of 487

0.89

0.74

0.00097

GOCC:1990904

Ribonucleoprotein complex

2 of 23

1.67

0.68

0.0461

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 66

1.76

3.23

2.26e-09

KW-0694

RNA-binding

6 of 66

1.69

2.68

8.53e-08

KW-0699

rRNA-binding

5 of 41

1.82

2.66

5.64e-07

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