STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MUS81MUS81 structure-specific endonuclease subunit. (547 aa)    
Predicted Functional Partners:
EME1
Crossover junction endonuclease EME1 isoform X1.
   
 0.999
FANCM
Fanconi anemia group M protein isoform X1.
    
 0.999
EME2
Essential meiotic structure-specific endonuclease subunit 2.
    
 0.998
WRN
Werner syndrome ATP-dependent helicase isoform X2.
   
 0.991
SLX4
Structure-specific endonuclease subunit SLX4.
   
 0.991
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.968
RMI1
recQ-mediated genome instability protein 1 isoform X1.
    
 0.962
FAAP24
Fanconi anemia core complex-associated protein 24 isoform X1.
   
 0.958
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
   
 0.956
BLM
Bloom syndrome protein isoform X1.
   
 0.953
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.