STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF1Insulin-like growth factor 1 transcript variant X4. (194 aa)    
Predicted Functional Partners:
IGFBP1
Insulin-like growth factor-binding protein 1.
    
 0.999
IGFBP3
Insulin-like growth factor-binding protein 3.
    
 0.999
IGF1R
Tyrosine-protein kinase receptor.
    
 0.999
IGFBP2
Insulin-like growth factor-binding protein 2.
    
 0.998
IGFBP5
Insulin-like growth factor-binding protein 5.
    
 0.998
INSR
Tyrosine-protein kinase receptor.
    
 0.995
IGFBP6
Insulin like growth factor binding protein 6.
    
 0.994
IGFBP4
Insulin-like growth factor-binding protein 4.
   
 0.985
IGF2R
Cation-independent mannose-6-phosphate receptor.
      
 0.984
GHRL
Appetite-regulating hormone.
     
 0.976
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.