Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apaHBis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (272 aa)    
Predicted Functional Partners:
SEM49290.1
Hypothetical protein.
   
 0.865
SEM14294.1
Protein of unknown function.
   
 0.851
SEL91769.1
SH3 domain protein.
  
    0.777
SEL91498.1
Stringent starvation protein B.
 
     0.661
SEM36277.1
PhoP regulatory network protein YrbL.
    
 0.629
SspA
RNA polymerase-associated protein; Belongs to the GST superfamily.
 
 
 
 0.612
menH
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
    
  0.611
SEM35067.1
Esterase.
    
  0.611
SEM07353.1
FKBP-type peptidyl-prolyl cis-trans isomerase FklB.
    
 
 0.608
SEM07650.1
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA.
    
 
 0.608
Your Current Organism:
Pasteurella skyensis
NCBI taxonomy Id: 97481
Other names: DSM 24204, NCIMB 13593, NCTC 13204, P. skyensis, Pasteurella skyensis Birkbeck et al. 2002, strain 95A1
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